Description of PK Solutions Pharmacokinetic Software
" Becoming the industry standard."
Michael C. Makoid, Creighton Univ. School of Pharmacy
" This is truly a lovely piece
D. Lazar, MD, PhD, Lazar Associates LLC
" Fills the gap for noncompartmental
of PK & ADME, Novartis Pharmaceuticals, Ltd.
" The best pharmacokinetics
software we have."
of Queensland, Department of Medicine
- The easiest pharmacokinetics data analysis software
- Excel-based program provides wide flexibility in a
familiar spreadsheet environment.
- Provides graphs and tables of all the most widely used pharmacokinetic
- Helps you analyze, record, compare, and report pharmacokinetic
and ADME study results.
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PK Solutions is an automated Excel-based program that
does single and multiple dose pharmacokinetic data analysis of concentration-time
data from biological samples (blood, serum, plasma, lymph, etc.) following
intravenous or extravascular routes of administration. The program provides
comprehensive tables of the most widely used and published pharmacokinetic
parameters with the ease of a few mouse clicks. PK Solutions calculates
results using noncompartmental (area) and compartmental (exponential terms)
methods without presuming any specific compartmental model. Multiple dose
and steady state parameters are automatically projected from single dose
The distinguishing features of PK Solutions are that it is easy, fast,
and comprehensive. The program works with both concentration-time data and
imported exponential terms. PK Solutions produces instant results suitable
novice and experts, without the need for programming.
PK Solutions makes pharmacokinetic data analysis
easy and fast. No programming required. Simply enter your data
and with a few mouse clicks on the analysis sheet you are done.
PK Solutions instantly computes and displays attractive graphs
and tables of results.
All Levels of Pharmacokinetic Experience
PK Solutions is used in over 67 countries
by researchers, clinicians, students, and others at all skill levels
who need a reliable and easy way to get pharmacokinetic data. Whether
you need PK data daily or only for an occasional report, PK Solutions
gives the needed results for the novice and professional user.
Coverage of PK Parameters
PK Solutions computes more PK parameters than
any other program. More than 75 single and multiple dose pharmacokinetic
results are computed from intravenous or extravascular dose data.
PK parameter calculations are based on two standard methods of
analysis: (1) curve-stripping (or method of residuals)
to derive the exponential terms that describe the blood level curve,
and (2) area under the curve calculations. PK
Solutions applies both methods where applicable and compares the
Interaction with Dynamic Updates
All graphs and formulas are dynamically linked
affording instant updates and immediate feedback when exploring
the effect of changes in data or other inputs. For example, changing
a dose interval gives an immediate redraw of the multiple dose
blood level curve. Explore 'What if?' questions. Dynamic interaction
helps you grasp the principles of pharmacokinetic analysis.
Changes - Compare Multiple Data Sets
Capture a complete listing of over 75 PK parameters
for each data set. You can capture and compare the results of up
to 256 data sets on a single, flexible form (and >65K in Excel 2007 and higher). A menu allows selection
of parameter groups to be displayed and printed. Print reports,
data tables, and graphs in color or black and white. Export or
copy results and graphics for inclusion in presentations or formal
PK Solutions includes the results of seven
test data sets taken from the literature. Comparison of the literature
values with those obtained by PK Solutions assures the scientific
validity of the program. The test data can also be used to verify
the reproducibility of calculations and the performance of the
software. PK Solutions is used in hundreds of regulated laboratories
throughout the world.
for Maximum Flexibility and Usefulness
PK Solutions is a Microsoft Excel program
that can run on PCs using any version of Windows (Windows 3.x,
9x, NT/2000, XP, Vista, 7, 8 and higher) as well as on Macintosh and Linux computers using Excel. Excel provides
a familiar working environment with extraordinary capabilities
for additional analyses, importing and exporting of data, and interaction
with other software. PK Solutions can be integrated with other
Microsoft Office documents, databases, and intranet platforms.
Reports and presentations of the results is easily accomplished
using standard Office procedures.
The PK Solution 2.0 User Guide is a complete
manual supplied in an attractive notebook. The guide clearly describes
and illustrates all program options and features. In addition,
the guide includes a description of all the pharmacokinetic parameters,
graphing functions, and formulas used by the program thereby providing
a useful compilation of pharmacokinetic equations in one place.
See the PK Equations page
for an excerpt from the guide describing the pharmacokinetic calculations
More About PK Solutions
Use the navigation bar at the top to learn more about PK Solutions.
of more information available on this site:
Please Contact us for additional information and inquiries.
David S. Farrier, Ph.D.
Summit Research Services
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