Pharmacokinetic Software for Research and Education

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Screen Shots and Features Tour of PK Solutions

  Multiple Dose Results - Oral or Extravascular Dose Route

• The Multiple Dose PK sheet uses the single dose results along with a user-defined dose interval (tau) to project kinetic values for multiple dosing.
• Like the single dose sheet, the multiple dose sheet is automatically configured and the results calculated when when the Define Terms button on the Data Analysis page is clicked.
• The results table and graph that initially appear on the Multiple Dose PK sheet vary to reflect the dose route selected during setup. The top screen shows the layout based on an "oral" or extravascular dose. The bottom screen shows the layout for an intravenous dose.
• By default, the initial display shows the calculated multiple dose results based on a dose interval set at the elimination half-life. Changing the tau value instantly recalculates the affected parameters and updates the graph.

  Multiple Dose Results - Intravenous Dose Route

• Screen shot of the Multiple Dose PK sheet that appears when the intravenous dose route is selected.
• The graph can be moved to reveal the underlying Notes using the blue rearrangement buttons.
• Options for user inputs and interactions are uniformly displayed in bold red type throughout PK Solutions. The intravenous multiple dose sheet contains a special section for Ad Hoc Intravenous Calculations, including three that allow user interaction.