Pharmacokinetic Software for Research and Education

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Screen Shots and Features Tour of PK Solutions

  Curve Simulation

• The Curve Fit sheet also contains a Plot Imported Terms work area. This is an optional work area and does not affect any of the other results.
• The purpose of this work area is to illustrate the concentration-time graph based on the sum of exponential terms that describe the data set. The intercept and rate constants for each exponential term can be manually input in the top table. Alternately, the "Copy Terms..." button will use the data in the Imported Exponential Terms table (Data Setup sheet).
• The chart display automatically updates with every change in the Import or Input Exponential Terms table.
• The values driving the chart display are shown in the table bottom table. This too, automatically updates.
• The literature frequently contains concentration expressions that appear similar to the following:
  C=-147*exp(-0.42*t) + 43*exp(-0.03*t)    With PK Solutions, you can input the disposition constants from up to three exponential terms as the source data for calculating all the PK results, and you can use this plot utility to even draw the original plasma level curve.